En 1932, Cannon publicó un libro titulado "The Wisdom of the Body" (La sabiduría del cuerpo), donde exploró cómo el cuerpo humano mantiene su equilibrio interno a pesar de los cambios externos. En este libro, Cannon describe cómo el cuerpo regula funciones como la temperatura, el pH, la glucemia y la hidratación, entre otras.
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